In animal studies, PFOA posed health hazards like:
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Serious changes in organs including the brain, prostate, liver, thymus, and kidneys, showing toxicity.
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Death of several rat pups that were exposed to PFOA.
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Changes in the pituitary in female rats, at all doses. The pituitary controls growth, reproduction, and many metabolic functions. Changes in the size of the pituitary are considered an indication of toxicity.
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PFOA has been associated with tumors in at least four different organs in animal tests, and has been implicated in an increase in prostate cancer in PFOA plant workers. 5
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